Anti-GALE/Galactowaldenase Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-13265R-A680
BOSSBS-13265R-A680EA 1190 CHF
BOSSBS-13265R-A680
Anti-GALE/Galactowaldenase Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataractsMore Product Information
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