D-Cycloserin, weißgraues Puder
Lieferant: ICN Biomedicals
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Achtung
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Synonyms:
D-4-Aminoisoxazolidin-3-on
, D(+)-Cycloserin
, (R)-(+)-Cycloserin
Synthetic Bactericidal Antibiotic. A structural analog of D-Alanine. A partial agonist at the glycine modulatory site of NMDA receptors; enhances learning and memory in several models of cognitive deficit; anticonvulsant (at high doses). Antibiotic against gram-negative bacteria that acts by inhibiting the synthesis of the cell wall (D-Ala peptide bond formation).
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Soluble in water (up to 100 mg/ml - clear, colorless to faint yellow solution), 96% ethanol (1 in 50 parts ethanol); slightly soluble in methanol or propylene glycol; practically insoluble in chloroform and ether.
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Formel:
C₃H₆N₂O₂ MW: 102,09 g/mol Lager Temperatur: Gefrierschrank |
MDL Number:
MFCD00005353 CAS-Nummer: 68-41-7 EINECS: 200-688-4 |
Spezifikation Testergebnisse
| Identity Test | Passes |
| Potency | ≥900 µg/mg |
| FTIR | Conforms to Standard |
| pH (2% aq soln) | 5,5 - 6,5 |
| Solubility (5% aq soln) | Clear, Colorless to Slightly Pink to Yellow Solution |
| Typical Working Concentration | 100-200 µg/ml. Prepare just before use using 0,1 M sodium phosphate buffer, pH 8,0, |
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