HMDS (1,1,1,3,3,3-Hexamethyldisilazan) Silylierungsreagenz, zur GC-Derivatisierung
Lieferant: MACHEREY-NAGEL
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Gefahr
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Synonyms:
Bis(trimethylsilyl)amin
MANA701240.510EA
60.9
CHF
MANA701240.510
MANA701240.650
HMDS (1,1,1,3,3,3-Hexamethyldisilazan) Silylierungsreagenz, zur GC-Derivatisierung
HMDS (1,1,1,3,3,3-Hexamethyldisilazan)
HMDS is weak TMS donor. If used as sole reagent, it is slow and not very effective. After addition of catalytic quantities (e.g., 1 %) of TMCS or as a mixture with TMCS it is a fast and quantitative reagent for trimethylsilylation of organic compounds.
- Silylation can be applied on many compounds
- Silylation reagents are easily prepared
- HMDS reagent mixed with TMCS catalyst shows fast and quantitative reaction
Aprotic solvents like acetonitrile, pyridine, dimethylformamide, carbon disulfide and dimethylacetamide are recommended for use with HMDS.
Formel:
(CH₃)₃SiNHSi(CH₃)₃ MW: 161,39 g/mol Siedepunkt: 126 °C (760 mm Hg) Dichte: 0,7742 g/cm³ (d20°/4°) |
MDL Number:
MFCD00008259 CAS-Nummer: 999-97-3 UN: 3316 ADR: 9,II |
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